Anaemia is a condition in which the number of red blood cells or the haemoglobin concentration within them is lower than normal. Haemoglobin is needed to carry oxygen and if you have too few or abnormal red blood cells, or not enough haemoglobin, there will be a decreased capacity of the blood to carry oxygen to the body’s tissues.
The ‘you are what you eat’ connection between food consumption and health outcomes is so well-established it’s practically irrefutable. Search ‘diet and disease’ on PubMed (the go-to database for scientific research) and you’ll get over 150,000 results – and that’s just one search term. There’s robust evidence that a diet rich in fruit, veg, wholegrains, fish and nuts can dial down your risk of heart disease, Type 2 diabetes, cancer and stroke, while dietary villains like soft drinks and processed meat do the opposite. You can drill down further, and link specific nutrients to health outcomes – for instance, we know insufficient iron causes anaemia, zinc promotes immunity, while magnesium regulates blood pressure.
The pathophysiology of anaemia.
"Anemia can be defined as a reduced absolute number of circulating red blood cells. In practice a low hemoglobin concentration or a low hematocrit is most widely accepted definition for anaemia. Red blood cells are the cells that carry oxygen around our body. Red blood cells also known as erythrocytes arise from myeloid progenitor cells in the bone marrow. Erythropoesis is the process of erythrocyte production. Myeloid progenitor cells become reticulocytes. This path is stimulated by hormones including erythropoietin. The reticulocyte enter blood stream 3 days later and matures to become a RBC in circulation. The mature RBC circulates for around 120 days, after which time it is removed from the circulation by the reticuloendothelial system. When performing a FBC or CBC, looking at Hb is the first step in diagnosing anaemia. One way to categorise anaemia is be looking at the mean corpuscular volume. Mean corpuscular volume (MCV) is the average size of a persons RBCs Therefore one way to categorize anaemia is using the MCV. You can have microcytic, Normocytic and marcocytic anaemia. Another way to classify anaemia is by looking at the pathophysiology
What is iron deficiency anemia? Anemia is a condition where there’s a decrease in the number of healthy red blood cells, or RBCs, in the body. So, iron deficiency anemia means anemia caused by a deficiency in iron. Iron deficiency anemia is also the most common type of anemia worldwide.
In this video, Amanda Haney will teach you about iron deficiency anemia, including what it is and how you can improve it by consuming foods high in iron.
Red blood cells carry hemoglobin, an iron-rich protein that attaches to oxygen in the lungs and carries it to tissues throughout the body. Anemia occurs when you do not have enough red blood cells or when your red blood cells do not function properly. It is diagnosed when a blood test shows a hemoglobin value of less than 13.5 gm/dl in a man or less than 12.0 gm/dl in a woman. Normal values for children vary with age.